The PAAD Study : Physical Activity and Alzheimer's Disease

paad study graphic

Researchers at the University of North Carolina at Greensboro are conducting research to determine if a person's genetic risk for Alzheimer's disease predicts the benefits they experience from exercise.

If you qualify to participate, you will be invited to participate in a FREE 8-month physical activity program.

The Principal Researcher is Dr. Jenny Etnier .

Media Coverage

Dr. Etnier was interviewed by on WFMY about the PAAD study. Read WFMY article .

Dr. Etnier was also interviewed by Dr. Matt Taylor of Health Talk, Rockingham County Radio, about Physical Activity and Alzheimer's Disease. Listen to interview below :

Inclusion criteria

  • Between 50-65 years of age .
  • Family history of Alzheimer's disease.
  • Currently not regularly physically active (i.e., exercising less than 30 min / day, 3 times / week over the past 3 months).
  • Intend to live in the Greensboro area for the next year.

Exclusion criteria

These will be determined through questionnaires and testing.
  • Display symptoms of cognitive impairment or depression.
  • Currently taking medications that affect thinking or that make is unsafe to exercise .
  • Unable to exercise for health reasons .
  • Uncorrected visual impairment.


  • Telephone interview to determine if meet inclusion criteria (~20 minutes).
  • Baseline testing at UNCG campus to further determine eligibility (2-3hrs).
  • Provision of a cheek swab to be used for genetic analysis.
  • Pre-test, mid-test, and post-test - to measure fitness and thinking abilities (~2hr each).
  • Participation in a free exercise program at UNCG campus 3 days per week for 8-months.


To be paid as gift cards.
  • Participants who complete baseline testing will receive $10.
  • Participants who complete pre - test, mid - test, and post - test sessions will receive $10 per session.
  • Participants who attend >=75% of exercise sessions over 8 weeks will receive $10.
  • Parking at UNCG will be paid for by PAAD.


University of North Carolina at Greensboro, Health and Human Performance Building.


If you are interested in participating, you may call, email , or submit the form below.
We look forward to hearing from you !

Please include :
  • Name
  • Phone number(s)
  • Email if you have one.
  • A good time for us to call you.
Phone : The PAAD hotline is 336-334-3275.
Email :

Or fill out the following form :